Pterosin D - CAS 34169-70-5
Catalog number: 34169-70-5
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Pterosin D is a natural sesquiterpenoids isolated from the rhizoma of Cibotium barometz (L.) J.Sm.
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1.[Sesquiterpenoids of Coniogramme maxima].
Chen Y;Liu S;Wang F Zhongguo Zhong Yao Za Zhi. 2012 Apr;37(7):946-50.
OBJECTIVE: ;To study sesquiterpenoids of Coniogramme maxima.;METHOD: ;Chemical constituents were separated by chromatography and their structures were identified according to physicochemical property and spectrum data.;RESULT: ;Fifteen compounds were separated by chromatography technique. Their structures were determined by spectral data, including 10 sesquiterpenoids as (3S)-pteroside D (1), epi-pterosin L (2), pterosin D (3), onitin (4), pterosin Z (5), onitisin (6), onitisin-glucopyranoside (7), onitin-15-O-beta-D-glucopyranoside (8), (2S,3R)-pterosin-L-2'-O-beta-D-glucopyranoside (9) and (3R)-peterosin D-3-O-beta-D-glucopyranoside (10). The other compounds were uracil (11), 3,4-dihydroxybenzaldehyde (12), 5-hydroxymethyl-2-furancarboxaldehyde (13), beta-sitosterol (14) and daucosterol (15).;CONCLUSION: ;The above 15 compounds are separated from C. maxima for the first time, including 9 compounds being first separated from genus Coniogramme.
2.Chemical constituents analysis and antidiabetic activity validation of four fern species from Taiwan.
Chen CY;Chiu FY;Lin Y;Huang WJ;Hsieh PS;Hsu FL Int J Mol Sci. 2015 Jan 22;16(2):2497-516. doi: 10.3390/ijms16022497.
Pterosins are abundant in ferns, and pterosin A was considered a novel activator of adenosine monophosphate-activated protein kinase, which is crucial for regulating blood glucose homeostasis. However, the distribution of pterosins in different species of ferns from various places in Taiwan is currently unclear. To address this question, the distribution of pterosins, glucose-uptake efficiency, and protective effects of pterosin A on β-cells were examined. Our results showed that three novel compounds, 13-chloro-spelosin 3-O-β-d-glucopyranoside (1), (3R)-Pterosin D 3-O-β-d-(3'-p-coumaroyl)-glucopyranoside (2), and (2R,3R)-Pterosin L 3-O-β-d-(3'-p-coumaroyl)-glucopyranoside (3), were isolated for the first time from four fern species (Ceratopteris thalictroides, Hypolepis punctata, Nephrolepis multiflora, and Pteridium revolutum) along with 27 known compounds. We also examined the distribution of these pterosin compounds in the mentioned fern species (except N. multiflora). Although all pterosin analogs exhibited the same effects in glucose uptake assays, pterosin A prevented cell death and reduced reactive oxygen species (ROS) production. This paper is the first report to provide new insights into the distribution of pterosins in ferns from Taiwan.
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CAS 34169-70-5 Pterosin D

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