Prothioconazole - CAS 178928-70-6
Catalog number: B0046-223338
Category: APIs
Molecular Formula:
C14H15Cl2N3OS
Molecular Weight:
344.3
COA:
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Description:
Prothioconazole is an antifungal agent that can be used as agricultural fungicide and herbicide.
Ordering Information
Catalog Number Size Price Stock Quantity
B0046-223338 1 g $168 In stock
B0046-223338 2.5 g $298 In stock
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Purity:
>95%
Appearance:
Pale Beige Solid
Synonyms:
2-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazole-3(2H)-thione
MSDS:
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Boiling Point:
486.7ºC at 760mmHg
Melting Point:
137-139ºC
Density:
1.5 g/cm3
InChIKey:
MNHVNIJQQRJYDH-UHFFFAOYSA-N
InChI:
InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)
Canonical SMILES:
C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl
1.Toxicokinetics and tissue distribution of prothioconazole in male adult Sprague-Dawley rats following a single oral administration.
Zhou F1, Dai L, Wei S, Cheng G, Li L. Xenobiotica. 2015 May;45(5):450-5. doi: 10.3109/00498254.2014.988771. Epub 2014 Dec 3.
1. Prothioconazole (PTC) is a new type of triazolinthione fungicide used worldwide. Despite its widespread use, the basic toxicokinetics (TK) information for health risk assessments of PTC is limited. 2. TK behavior and metabolism studies of PTC were performed in male adult Sprague Dawley (SD) rats after a single oral administration. Serial blood and tissue samples were analyzed for their PTC content by high-performance liquid chromatography (HPLC) to obtain comprehensive time-course data for estimation of TK parameters. 3. PTC was rapidly but incompletely absorbed from the gastrointestinal tract of fasted adult rats. It was widely distributed in all parts of body, but demonstrated little tendency to accumulate. And PTC was excreted mainly in the form of parent compound. 4. The detection of PTC in brain and testis proved that further investigations are required to determine whether PTC could result in neurotoxicity and male reproductive toxicity.
2.Distribution of prothioconazole and tebuconazole between wheat ears and flag leaves following fungicide spraying with different nozzle types at flowering.
Lehoczki-Krsjak S1, Varga M, Mesterházy Á. Pest Manag Sci. 2015 Jan;71(1):105-13. doi: 10.1002/ps.3774. Epub 2014 Apr 9.
BACKGROUND: Wheat ears are difficult targets from the aspect of fungicide spraying. Sideward-spraying nozzle types may enhance the ear coverage, which may possibly lead to higher effectiveness in the management of Fusarium head blight (FHB).
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CAS 178928-70-6 Prothioconazole

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