Propionyl-L-Carnitine HCl - CAS 119793-66-7
Catalog number: B0084-055506
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C10H20ClNO4
Molecular Weight:
253.73
COA:
Inquire
Targets:
Others
Description:
The hydrochloride salt form of L-Propionylcarnitine which has been found to be related to mitochondrial metabolism so that could be used in the treatment deterioration of renal function and sorts of other diseases.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-055506 250 mg $199 In stock
Bulk Inquiry
Purity:
95%
Appearance:
White Solid
Synonyms:
PROPIONYL-L-CARNITINE CHLORIDE;PROPIONYL L-CARNITINE HCL;PROPIONYL-L-CARNITINE HYDROCHLORIDE;PROPIONYL-LEVO-CARNITINE HYDROCHLORIDE;(r)-2-propionyl-3-(trimethylaminium)butanoic acid chloride;Propionyl L-Carnitine
Solubility:
DMSO: ≥ 2.5 mg/mL
Storage:
Store at 0ºC
MSDS:
Inquire
Application:
The hydrochloride salt form of L-Propionylcarnitine which has been found to be related to mitochondrial metabolism so that could be used in the treatment deterioration of renal function and sorts of other diseases.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
KTFMPDDJYRFWQE-DDWIOCJRSA-N
InChI:
InChI=1S/C10H19NO4.ClH/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4;/h8H,5-7H2,1-4H3;1H/t8-;/m1./s1
Canonical SMILES:
CCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-]
1.Plasma pharmacokinetics and gastrointestinal transit of a new propionyl-L-carnitine controlled release formulation.
Wagner CC1, Rusca A, Kletter K, Tschurlovits M, Pace S, Longo A, Pedrani M, Villa R, Frimonti E, Müller M, Brunner M. Xenobiotica. 2011 Nov;41(11):988-95. doi: 10.3109/00498254.2011.597454. Epub 2011 Aug 3.
Propionyl-L-carnitine is a naturally occurring analogue of L-carnitine (LC) produced in the body. PLC administration has shown beneficial effects in cardiovascular pathologies. In ulcerative colitis (UC), oral PLC treatment increased clinical presentation and positively influenced colon histology. In the present study, the MMX Multi Matrix System® (MMX™) was used as drug delivery strategy for targeted PLC colon delivery. A pharmacoscintigraphic study (n = 6 healthy volunteers) described release characteristics of two MMX-PLC-HCl controlled release 500 mg tablets. A pharmacokinetic (PK) parallel group study (n = 24) determined safety, plasma PLC concentrations and PK parameters after single and multiple doses. Gastrointestinal transit was slow and variable. The colon was the main site of PLC release and absorption. After single 500 or 1000 mg PLC doses plasma PLC and LC increased up to 2.6 and 1.2-1.3-fold compared to baseline. Multiple doses of 500 and 1000 mg twice a day over 7 days did not significantly increase maximum plasma concentrations of PLC or LC with respect to concentrations achieved after single dose administration.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 599151-35-6 FQI 1

FQI 1
(CAS: 599151-35-6)

FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis i...

CAS 83-88-5 Riboflavin

Riboflavin
(CAS: 83-88-5)

Riboflavin, also known as vitamin B2, is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.<br/>Vitamin supplem...

CAS 3055-99-0 Polidocanol

Polidocanol
(CAS: 3055-99-0)

A nonionic surfactant.

CAS 117505-80-3 Neuromedin U (rat)

Neuromedin U (rat)
(CAS: 117505-80-3)

Neuromedin U, a structurally highly conserved neuropeptide, is ubiquitously distributed, with highest levels found in the gastrointestinal tract and pituitary. ...

CAS 2998-57-4 Estramustine

Estramustine
(CAS: 2998-57-4)

Estramustine, a derivative of estradiol, is an alkylating antineoplastic agent that is used in the treatment of prostate cancer throughout the world.

CAS 127967-03-7 PD 131628

PD 131628
(CAS: 127967-03-7)

PD 131628 is a new fluoroquinolone as the bioactive form of PD 131112 which is a antibacterial agent originated by Pfizer. PD 131112 can be used for the treatme...

CAS 4373-41-5 Maslinic acid

Maslinic acid
(CAS: 4373-41-5)

Maslinic acid is a pentacyclic triterpene found in a variety of natural sources. It exerts a wide range of biological activities, such as antitumor, antidiabeti...

CAS 1203680-76-5 AS 1949490

AS 1949490
(CAS: 1203680-76-5)

AS1949490 has been found to be a selective SHIP2 phosphatase inhibitor and show antidiabetic activities.

Chemical Structure

CAS 119793-66-7 Propionyl-L-Carnitine HCl

Quick Inquiry

Verification code

Featured Items