Pralidoxime chloride - CAS 51-15-0
Catalog number: 51-15-0
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C7H9ClN2O
Molecular Weight:
172.61
COA:
Inquire
Targets:
AChE
Description:
Pralidoxime is an antidote to organophosphate pesticides, reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Purity:
≥98%
Appearance:
White to off-white Solid
Synonyms:
1-Methylpyridinium-2-aldoxime Chloride; (1-methylpyridin-2-ylidene)methyl-oxoazanium;chloride
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Combat poisoning from organophosphates and nerve agents
Quality Standard:
Enterprise Standard/USP
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Melting Point:
>215 °C
InChIKey:
HIGSLXSBYYMVKI-UHFFFAOYSA-N
InChI:
1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H
Canonical SMILES:
CN1C=CC=CC1=C[NH+]=O.[Cl-]
1.[The comparison of clinical manifestation of organophosphorus pesticide poisoning (OPP) between oral exposure and occupational exposure in field work].
Hu XZ1, Lu ZQ, Sun LF, Wang Z. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011 May;29(5):378-80.
OBJECTIVE: To investigate the differences of clinical manifestation and therapy of organophosphorus pesticide poisoning (OPP) between oral exposure and occupational exposure in field work.
2.[The observations of curative efficacy of rhubarb combined with blood purification on treatment patients with severe acute organophosphorus pesticide poisoning].
Yu HJ1, Shen DF, Liu B, Shi YC. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2012 Apr;30(4):304-6.
OBJECTIVE: To observe the curative efficacy of rhubarb, montmorillonite powder combined with blood purification on treatment for patients with severe acute organophosphorus pesticide poisoning (AOPP).
3.Lipopolysaccharide increased the acute toxicity of the Rhizoma coptidis extract in mice by increasing the systemic exposure to Rhizoma coptidis alkaloids.
Ma BL1, Ma YM, Gao CL, Wu JS, Qiu FR, Wang CH, Wang XH. J Ethnopharmacol. 2011 Oct 31;138(1):169-74. doi: 10.1016/j.jep.2011.08.074. Epub 2011 Sep 8.
ETHNOPHARMACOLOGICAL RELEVANCE: Rhizoma coptidis is used as an antidysenteric in clinics in China. However, patients suffering from dysentery are susceptible to the acute toxicity of Rhizoma coptidis. The current study investigates the effects of lipopolysaccharide (LPS), which are a key pathogenic factor in dysentery, on the acute toxicity of a Rhizoma coptidis extract in mice; possible mechanisms are proposed.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related AChE Products


CAS 122892-31-3 Itopride hydrochloride

Itopride hydrochloride
(CAS: 122892-31-3)

Reversible AChE inhibitor. D2 receptor antagonist. Raises motilin and somatostatin levels. Lowers CCK levels. Shows gastroprokinetic effects in vivo. Orally act...

CAS 510-77-0 Galanthaminone

Galanthaminone
(CAS: 510-77-0)

Galantamine is a competitive and reversible cholinesterase(AChE) inhibitor, which is used for the treatment of mild to moderate Alzheimer's disease and various ...

CAS 59-99-4 Neostigmine

Neostigmine
(CAS: 59-99-4)

Neostigmine is a parasympathomimetic compound, which acts as a reversible acetylcholinesterase inhibitor. It is used in the treatment of myasthenia gravis, ogil...

CI 1002
(CAS: 149028-28-4)

CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction...

CAS 120014-06-4 Donepezil

Donepezil
(CAS: 120014-06-4)

Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to se...

CAS 149062-75-9 CI-1002 hydrochloride

CI-1002 hydrochloride
(CAS: 149062-75-9)

The hydrochloride salt form of CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effectiv...

CAS 101246-66-6 Phenserine

Phenserine
(CAS: 101246-66-6)

Phenserine, an analog of physostigmine, is an acetylcholinesterase (AChE) inhibitor (IC50= 24 nM) potentially for the treatment of Alzheimer Disease (AD).

Icopezil maleate
(CAS: 145815-98-1)

The maleate salt form of Icopezil, a benzoxazol derivative, has been found to be an acetylcholinesterase inhibitor and was once studied for the treatment of Alz...

Chemical Structure

CAS 51-15-0 Pralidoxime chloride

Quick Inquiry

Verification code

Featured Items