Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
5-HT Receptor
PR-073 is a novel 5-HT7 antagonist, which can inhibit immune responses and treat inflammatory bowel disease (IBD). Preclinical studies demonstrated that PR-073 has a high potency (Ki = 89 nM) and selectivity. Its oral bioavailability in the mouse is 17% as well as half-life is 3.4 h after oral dosing.
Brife Description:
5-HT7 antagonist, inflammatory bowel disease (IBD)
PR-073; PR 073; PR073
the treatment of inflammatory bowel disease (IBD)
Current Developer:
Temple University; Praeventix
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related 5-HT Receptor Products

(CAS: 477930-31-7)

(S)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the ...

CAS 64022-27-1 MK212

(CAS: 64022-27-1)

MK212 is a 5HT2C-receptor agonist. It exhibited anxiolytic activity in mice at low doses. It is a serotonin agonist. It could promote the secretion of serum pro...

CAS 98206-09-8 Eltoprazine hydrochloride

Eltoprazine hydrochloride
(CAS: 98206-09-8)

Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B re...

CAS 510733-97-8 ATC 0175 hydrochloride

ATC 0175 hydrochloride
(CAS: 510733-97-8)

The hydrochloride salt form of ATC 0175, which has been found to be a MCHR1, SR-1A and SR-2B inhibitor and probably show anxiolytic and antidepressant activitie...

CAS 1465-16-3 1-Methylpsilocin

(CAS: 1465-16-3)

1-Methylpsilocin is a potent and selective 5-HT2C agonist (IC50= 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). It is acting at 5-HT2A sites but i...

CAS 1417343-80-6 SDZ SER 082 fumarate

SDZ SER 082 fumarate
(CAS: 1417343-80-6)

SDZ SER 082 fumarate is a selective 5-HT2B/2C receptor antagonist with low affinity for 5-HT1A receptors. SDZ SER 082 fumarate inhibits [3H]-mesulergine binding...

CAS 26328-11-0 (S)-(-)-Pindolol

(CAS: 26328-11-0)

(S)-(-)-Pindolol, the more active enantiomer of pindolol, is 5-HT1A/1B receptor antagonist, with roughly equal affinity for each subtype.

CAS 168986-60-5 RS 67333 hydrochloride

RS 67333 hydrochloride
(CAS: 168986-60-5)

RS 67333 hydrochloride is a selective, high affinity partial agonist toward 5-HT4 receptor with pKi values of 8.7 at 5-HT4 sites in guinea pig striatum and > 6 ...

Quick Inquiry

Verification code

Featured Items