|Description||PR-073 is a novel 5-HT7 antagonist, which can inhibit immune responses and treat inflammatory bowel disease (IBD). Preclinical studies demonstrated that PR-073 has a high potency (Ki = 89 nM) and selectivity. Its oral bioavailability in the mouse is 17% as well as half-life is 3.4 h after oral dosing.|
|Brife Description||5-HT7 antagonist, inflammatory bowel disease (IBD)|
|Synonyms||PR-073; PR 073; PR073|
|Application||the treatment of inflammatory bowel disease (IBD)|
|Current Developer||Temple University; Praeventix|
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