|Description||PPTN, a 4,7-disubstituted 2-naphthoic acid derivative, is a high affinity and selective P2Y14 antagonist (KB = 434 pM) with >10,000-fold selectivity for P2Y14 over other P2Y receptors. PPTN blocks UDP-glucose–promoted chemotaxis of human neutrophils and does so across a concentration range consistent with its KB determined in the P2Y14-R–expressing cell line.|
|Purity||≥98% by HPLC|
|Synonyms||4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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