PPTN hydrochloride
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
P2Y Receptor
PPTN, a 4,7-disubstituted 2-naphthoic acid derivative, is a high affinity and selective P2Y14 antagonist (KB = 434 pM) with >10,000-fold selectivity for P2Y14 over other P2Y receptors. PPTN blocks UDP-glucose–promoted chemotaxis of human neutrophils and does so across a concentration range consistent with its KB determined in the P2Y14-R–expressing cell line.
≥98% by HPLC
4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride
Store in a cool and dry place (or refer to the Certificate of Analysis).
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