|Targets||5-HT Receptor | Dopamine Receptor|
|Description||PNU 96415E, chemically unrelated to clozapine, exhibits high affinity for dopamine D4 and serotonergic 5-HT2A receptors and relatively weak affinity at D2 receptors (Ki= 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D4, 5-HT2A, 5-HT1A, α1, D2, D3, D1, α2 and muscarinic receptors respectively). PNU-96415E has a profile of behavioral effects in rodents very similar to that of clozapine, including complete discriminative stimulus generalization.|
|Purity||≥98% by HPLC|
|Synonyms||PNU 96415E; PNU96415E; PNU-96415E; 1-[2-(3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-4-(4-fluorophenyl)piperazine dihydrochloride|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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