|Description||PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin).|
Condelphine was isolated from the roots of Delphinium denudatum. A nicotinic receptor antagonist at the neuromuscular junction and ganglioblocking agent.
Tubulysin M is a Tubulysin D analog with potential anti-cancer properties, used as the cytotoxic component in antibody-drug conjugates.
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
β-Pompilidotoxin slows the inactivation of neuronal Navs. β-Pompilidotoxin was isolated from the venoms of two wasps, Anoplius amariensis and Batozonellus macul...
Sevedindione presents an antiarrhythmic activity on arrhythmias caused by Aconitine.
Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
A muscarinic receptors antagonist.
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Steroidal Alkaloid from Convolvulus krauseanus
Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Synthetic, a weak AChR antagonist.
alpha and beta Adrenoreceptors subtypes agonist; MAO inhibitor. Alkaloid derivative of l-Ephedrine from plants of the Ephedra genus, Ephedraceae.
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.
DC-1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Nemorubicin, is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity pro...
A natural compound extracted from Phellodendron chinense, exhibits a near planar framework
PLA2 Apis mellifera
Active enzyme isolated from bee venom · One unit of enzyme hydrolyzes one µmol of Diheptanoyl Thio-PC per minute at 25°C.
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...