|Description||Pipobroman (trade names Vercite, Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. It is marketed by Abbott Laboratories. Pipobroman (PB) has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemia (ET).|
This active molecular is a bio-active chemical and detailed information has not been published yet.
A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM), which attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Stu...
Diniconazol is a chemical compound belongs to chlorine group of conazole. It is used as fungicide. It inhibited lanosterol 14 alpha-demethylation catalyzed by a...
RETF-4NA is a sensitive substrate for chymase when free or bound to α2M. It is selectively hydrolyzed by chymase but not by cathepsin G.
KLS-13019, an azetidine derivative, could be a neuroprotective agent and has been found to exbihit much more effective than cannabidiol.
Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various d...
Cgp-17520 is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd.
IKarisoside A is a natural compound isolated from Epimedium koreanum, which has anti-inflammatory properties.
Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant.
Gemilukast disodium salt
Gemilukast, also known as ONO-6950, is an orally active dual CysLT1 and CysLT2 antagonist. Gemilukast exhibited antagonist activities with IC50 values of 1.7 an...
Verbascoside is a bioactive polyphenol from olive oil mill wastewater with known antioxidant activity, which is a protein kinase C inhibitor.
PF 06424439 is a potent, selective and orally bioavailable Diacylglycerol Acyltransferase 2 ( DGAT2) inhibitor with DGAT2 IC50 ± SEM (nM) (human/rat/dog) 14 ± 1...
Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 select...
Methimazole (also known as Tapazole or Thiamazole or MMI) is an antithyroid drug,and part of the thioamide group. Like its counterpart propylthiouracil, a major...
A 196 is a potent and selective inhibitor of SUV420H1/H2 (IC50 = 25 and 144 nM, respectively) with 100-fold selectivity over other histone methyltransferases an...
An oxobutyric acid derivative which is used for stimulating gastro-intestinal function.
Gynostemma Extract is a saponins extract derived from the Gynostemma pentaphyllum.
3-Pyridinemethanol, an aromatic alcohol compound, is a widely used in the synthesis of some inhibitors like Chk1 and histone deacetylase inhibitors.
CB 3731 can be used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase.
Azelaic acid, produced by ozone cracking of unsaturated fatty acid, could be commonly used in grease, cosmetics and pharmaceuticals.