|Description||Piperine, which can be found in the fruits of Piper nigrum L, is a potential agonist of PXR and an inducer of PXR, which may induce CYP3A4 gene expression at the mRNA and protein levels. These results establish that Piperine may contribute to prevention or reduction of colonic inflammation. The ability of Piperine to inhibit several key signaling pathways involved in T lymphocyte activation and the acquisition of effector function suggests that Piperine might be useful in the management of T lymphocyte-mediated autoimmune and chronic inflammatory disorders. Piperine displays the more anti-oxidative, anti-apoptotic and chemo-protective properties in the DLM induced splenic apoptosis as compared to curcumin.|
|Synonyms||PIPERINE; N-PIPEROYLPIPERIDIN; (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine; FEMA 2909; 5-BENZO[1,3]DIOXOL-5-YL-1-PIPERIDIN-1-YL-PENTA-2,4-DIEN-1-ONE; 1-PIPERONYLPIPERIDINE; 1-PIPEROYLPIPERIDINE; 1-PIPERYLPIPERIDINE|
|Quality Standard||Enterprise Standard|
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