|Description||Physostigmine salicylate is a cholinesterase inhibitor that can cross blood-brain barrier. It forms slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). It has been used to improve cognitive ability and treat glaucoma.|
|B0084-028331||250 mg||$899||In stock|
|Synonyms||[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate (2-hydroxybenzoic acid) salt|
|Melting Point||>175°C (dec.)|
NDT 9513727 is a C5a receptor (C5aR) antagonist with IC50 value of 11.6 nM. NDT 9513727 can inhibit C5a-induced neutropenia in gerbil and cynomolgus macaque. In...
GSK-114 is a potent and selective TNNI3K inhibitor (TNNI3 IC50 = 25nM; B-RafV600E IC50 = 1000 nM). GSK-114 displays significant bias (40-fold) for TNNI3K over B...
Veratramine is useful as a signal transduction inhibitor for treating tumors.
AT-584, an azoniatricyclo compound, could have potential biological activity in pharmaceutical studies.
This active molecular is an potential cognitive enhancer originated by Bristol-Myers Squibb. Mechanism of Action is not identified. Bmy 21502 is also a nootropi...
PPNDS is a potent and selective P2X1 receptor antagonist (pKB = 7.43 in rat vas deferens). PNDS is approximately 50-fold less selective for P2Y1R and does not i...
TMPA is an antagonist of nuclear receptor Nur77 (Kd = 1.45 ± 0.35 μM) and LKB1 interaction.
APC-366, an amino acid derivative, has been found to be a mast cell tryptase inhibitor and was once studied against asthma by Celera Genomics Group. Ki: 7.1 μM.