PF-543 hydrochloride - CAS 1706522-79-3
Catalog number: 1706522-79-3
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C27H31NO4S.HCl
Molecular Weight:
502.07
COA:
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Targets:
Sphingosine 1 Phosphate Receptor
Description:
The hydrochloride salt form of PF-543, a novel SphK1 inhibitor that could exhibit activity in induceing necrosis in human colorectal cancer cells in biological studies. IC50: 2 nM; Ki: 3.6 nM.
Purity:
98%
Appearance:
Beige Solid
Synonyms:
PF-543 hydrochloride; PF 543 hydrochloride; PF543 hydrochloride; (2R)-1-[[4-[[3-Methyl-5-[(phenylsulfonyl)methyl]phenoxy]methyl]phenyl]methyl]-2-pyrrolidinemethanol Hydrochloride
Solubility:
DMSO: 100 mM
Storage:
Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
MSDS:
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Quality Standard:
In-house standard
Quantity:
Milligram-Grams
InChIKey:
WNKWAZFYPZMDGJ-VQIWEWKSSA-N
InChI:
InChI=1S/C27H31NO4S.ClH/c1-21-14-24(20-33(30,31)27-7-3-2-4-8-27)16-26(15-21)32-19-23-11-9-22(10-12-23)17-28-13-5-6-25(28)18-29;/h2-4,7-12,14-16,25,29H,5-6,13,17-20H2,1H3;1H/t25-;/m1./s1
Canonical SMILES:
CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4.Cl
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