|Description||PF 429242 is a reversible, competitive, cell permeable inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM) without disrupting a panel of serine proteases. Some studies reported that the inhibition of SKI-1/S1P, a master lipo- 387 genic regulator, could impair HCV genome replication, lipid droplet 388 homeostasis and the production of infectious HCV virions.|
|Brife Description||A competitive inhibitor of SREBP site 1 protease (IC50 = 0.175 μM)|
|Synonyms||PF-429242; PF 429242; PF429242. Benzamide, 4-[(diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-; 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide|
|Solubility||Soluble to 50 mM in water and to 50 mM in DMSO|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years).|
|Shelf Life||2 years|
|Boiling Point||562.2±50.0 °C | Condition: Press: 760 Torr|
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