|Description||PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs.|
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be h...
Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production d...
A terpenoid complex ester , from plants of the Umbelliferae family, a substance presenting an estrogenic activity.
α-conotoxin GI (alpha-conotoxin GI) is a conopeptide that has been isolated from the venom of the cone snail Conus geographus. α-conotoxin GI is a competitive a...
Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Quinoline alkaloid, extracted from Haplophyllum bucharicum (Rutacae)
Synthetic., a GABA-gated chloride channel blocker, non-competitive GABA antagonist in mammals.
Seco-Duocarmycin CN is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Alkaloid, extracted from Thalictrum isopyroide.
Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
alpha and beta Adrenoreceptors subtypes agonist; MAO inhibitor. Alkaloid derivative of l-Ephedrine from plants of the Ephedra genus, Ephedraceae.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Extract from plants of the Leguminosae family, an antiatherosclerotic and angioprotective, reduces platelet aggregation.
Alkaloid, Tetrahydroisoquinoline, Active dopamine metabolite, Cholinesterase inhibitor
Muscarinic toxin 2 (MT2) is one member of a family of small peptides of 65 amino acid residues of around 7076 daltons in molecular weight derived from the venom...
An inhibitor of serine proteinases of broad spectrum.
a CNS stimulant. Alkaloid, , purified from plants of Coffea genus, Rubiaceae.
Carothane complex ester , from plants of the Umbelliferae family.
A cardioselective M2-cholinoblocking compound semi-synthetic derivative of Imperialine alkaloid Derived from base alkaloid Imperialine, isolated from the plant ...