PE 154 - CAS 1192750-33-6
Category: Inhibitor
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Molecular Formula:
C35H35N5O4
Molecular Weight:
589.68
COA:
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Targets:
AChE | Amyloid-β
Description:
PE 154 is a fluorescent inhibitor of both AChE and BChE with IC50 values of 280 pM and 16 nM. PE 154 targets and labels β-amyloid plaques in histochemical analysis.
Purity:
≥97% by HPLC
Synonyms:
PE 154; PE154; PE-154; 4-[[[7-(Diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid 2-(1,2,3,4-tetrahydro-9-acridinyl)hydrazide
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
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InChIKey:
CYZIIGRHLSZNAV-SGWCAAJKSA-N
InChI:
InChI=1S/C35H35N5O4/c1-3-40(4-2)24-17-18-27-31(20-24)44-35(43)28(34(27)42)21-36-23-15-13-22(14-16-23)19-32(41)38-39-33-25-9-5-7-11-29(25)37-30-12-8-6-10-26(30)33/h5,7,9,11,13-18,20-21,36H,3-4,6,8,10,12,19H2,1-2H3,(H,37,39)(H,38,41)/b28-21+
Canonical SMILES:
CCN(CC)C1=CC2=C(C=C1)C(=O)C(=CNC3=CC=C(C=C3)CC(=O)NNC4=C5CCCCC5=NC6=CC=CC=C64)C(=O)O2
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Chemical Structure

CAS 1192750-33-6 PE 154

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