|Description||PDE-9 inhibitor is useful for neurodegenerative diseases.|
|Synonyms||PDE 9 inhibitor; PDE9 inhibitor; PDE-9 inhibitor|
A N-desmethyl analogue of the human PDE5 inhibitor Tadalafil. A potential antiplasmodial drug.
(S)-C33 is a potent and selective PDE9 inhibitor (IC50 = 11 nM).
Vardenafil, also called as Levitra and Nuviva, is a phosphodiesterase inhibitor that is selective for PDE5 and PDE1 (IC50 = 0.7 and 180 nM, respectively).
PDE1-IN-2 is an inhibitor of PDE1 that has IC50 values of 6, 140 and 164 nM for PDE1C, PDE1B and PDE1A, respectvely.
Small molecule inhibitor of the KRAS–PDEδ interaction that impairs oncogenic KRAS signalling by altering its localization to endomembranes (in cell Kd value 41 ...
Win-62005 competitively and selectively inhibits cyclic GMP-inhibitable low Km cyclic AMP phosphodiesterase (PDE III) from rat heart and canine aorta (Kis= 25 a...
PDE1-IN-1 is a potent PDE1 inhibitor and neuroprotective agent.
Filaminast is a Type 4 cyclic nucleotide phosphodiesterase inhibitor. It is an analog of rolipram which served as a prototype molecule for several development e...