PBD dimer - CAS 1222490-34-7
Category: ADCs
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C42H39N5O7
Molecular Weight:
725.79
COA:
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Tag:
ADCs Cytotoxin
Description:
PBD dimer is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
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Purity:
≥95%
Appearance:
Soild powder
Synonyms:
8-(3-((2-(4-Aminophenyl)-7-methoxy-5-oxo-1,11abeta-dihydro-5H-pyrrolo(2,1-C)(1,4)benzodiazepine-8-yl)oxy)propoxy)-7-methoxy-2-(4-methoxyphenyl)-1,11abeta-dihydro-5H-pyrrolo(2,1-C)(1,4)benzodiazepine-5-one;
MSDS:
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InChIKey:
OMRPLUKQNWNZAV-CONSDPRKSA-N
InChI:
InChI=1S/C42H39N5O7/c1-50-32-11-7-26(8-12-32)28-16-31-22-45-36-20-40(38(52-3)18-34(36)42(49)47(31)24-28)54-14-4-13-53-39-19-35-33(17-37(39)51-2)41(48)46-23-27(15-30(46)21-44-35)25-5-9-29(43)10-6-25/h5-12,17-24,30-31H,4,13-16,43H2,1-3H3/t30-,31-/m0/s1
Canonical SMILES:
COc1ccc(cc1)C2=CN3[C@@H](C2)C=Nc4cc(OCCCOc5cc6N=C[C@@H]7CC(=CN7C(=O)c6cc5OC)c8ccc(N)cc8)c(OC)cc4C3=O
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