|Structure\Application||Other modified nucleotides|
|Description||pApG is a metabolite of 3'3'-cGAMP, the bacterial second messenger, which is generated by specific PDEs in Vibrio cholerae. pApG does not bind to the c-diGMP-I riboswitch.|
|Purity||≥ 95% by HPLC|
|Synonyms||5'- Phosphoadenylyl- (3' −≥ 5')- guanosine, sodium salt|
GpCp is an analogue of GDP and has been found to be hydrolytically stable.
UDP-Gel is the UDP coupled to a polymeric gel by the terminal phosphate, which is used in the affinity purification of galactosyltransferases.
6-(1-MeBu)-ATP is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
ddCTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddCTP is commonly used to termina...
GpAp is a synthetic linear dinucleotide not binding to the c-diGMP-I riboswitch.
BzBzATP (BzATP) is a P2X7 receptor agonist exhibits high potency at P2X1 receptor (pEC50 = 8.7).
6-PhEt-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach.
TMP-CP is a non-hydrolytic analogue of thymidine-5'-diphosphate and an inhibitor of thymidine kinase. It is also used as a starting structure in the synthesis o...
2-Hydroxy-dATP is an oxidized form of dATP with a mutagenic effect, which is generated by being incorporated opposite G by Escherichia coli DNA polymerase III.