|Description||Palmitoylethanolamide is an endogenous cannabinoid found in brain, liver, and other mammalian tissues. It is a weak ligand of the cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptors, and a selective GPR55 agonist (EC50 values are 4, 19 800 and > 30 000 nM at GPR55, CB2 and CB1 receptors respectively).
Nutritional supplement in health care products.
|Synonyms||N-(2-Hydroxyethyl)hexadecanamide; Palmidrol; PEA|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Application||Ingredient of health care products.|
AM 1714, a synthetic cannabimimetic indole derivative, is a potent and selective agonist for the cannabinoid receptor.
AM 2232, a synthetic cannabimimetic indole derivative, is a potent and selective agonist for the cannabinoid receptor, with Ki values of 0.28 and 1.48 nM for th...
Jd-5037 is a peripherally-restricted cannabinoid inverse agonist at CB1 receptors that can be used as an anti-obesity drug, with a 700-fold higher affinity comp...
JTE 907 is a highly selective cannabinoid CB2 receptor inverse agonist and has been found to exhibit anti-inflammatory properties.
Arvanil is a vanilloid TRPV1 (VR1) and cannabinoid CB1 agonist with Ki values of 0.3 and 0.5 μM respectively. It increases lung tidal volume, diaphragm activity...
Rosonabant is a CB1 receptor antagonist/inverse agonist originated by Esteve. It is an appetite suppressant for the treatment of obesity. But development of the...
LEI 101 hydrochloride is a CB2 partial agonist with pEC50 value of 8.0. It shows antinociceptive activity in a rat neuropathic pain model. LEI 101 hydrochloride...
Hemopressin (rat) is a bioactive endogenous peptide substrate for endopeptidase 24.15, neurolysin and ACE (Ki = 27.76, 3.43 and 1.87 μM, respectively). Hemopres...