|Description||OUP16 is a potent and selective histamine H4 receptor(hH4R) agonist with 40-fold selectivity over the hH3R and superior to its (2S,5S)-configured optical antipode. It expressed in various cells of the immune system. It palys a role in inflammatory, autoimmune, and allergic disorders.|
|Synonyms||OUP-16;Guanidine, N-cyano-N''-methyl-N'-[[(2R,5R)-tetrahydro-5-(1H-imidazol-5-yl)-2-furanyl]methyl]-, rel-|
|Solubility||10 mM in DMSO|
|Application||OUP16 palys a role in inflammatory, autoimmune, and allergic disorders.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||492.2±55.0 °C | Condition: Press: 760 Torr|
|Density||1.38±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
KDM5A-IN-1, a pyrrolidine amide compound, is an inhibitor histone demethylases.
Mianserin Hydrochloride is a psychoactive drug of the tetracyclic antidepressant.It is classified as a noradrenergic and specific serotonergic antidepressant (N...
The dihydrochloride salt form of Mizolastine which is effective in the treatment of seasonal allergic rhinitis, perennial allergic rhinitis and other allergy sy...
Mianserin is a tetracyclic second generation antidepressant. It has the same efficacy as the tricyclics, but has no anticholinergic and cardiovascular side-effe...
Famotidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroe...
Betahistine is a histamine H3 receptors inhibitor with IC50 of 1.9 μM.
Mebhydroline Napadisylate is an antihistamine used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allerg...
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.
VUF10460 is a specific non-imidazole histamine H4 receptor agonist (pKi= 7.46, 8.22 for rat H4 receptor and human H4 receptor respectively) with 50-fold selecti...
METHDILAZINE HYDROCHLORIDE (200 MG)
This active molecular is a first-generation antihistamine and belongs to phenothiazine class. Methdilazine Hydrochloride is a Histamine H1 receptor antagonist w...
Metiamide is developed from another burimamide, used as a histamine H2 receptor antagonist.
This active molecular is a imidazolylpropylguanidine type compound as a hH4R agonist (histamine H4 receptor agonist) showing negligible hH1R and hH2R activities...
Loratadine is a histamine H1 receptor antagonist, used to treat allergies. It also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...
Azelastine, a phthalazine derivative, is a potent, second-generation, selective, histamine antagonist used as a first line therapy of mild intermittent.
Bavisant dihydrochloride is the dihydrochloride form of Bavisant, which is a highly selective, orally active antagonist of the human H3 receptor. It may be used...
This active molecular is a potent histamine H3 inverse antagonist. Current antipsychotic treatments have little impact on the cognitive deficits associated with...
The hydrochloride salt form of Clemizole that has hepatitis C antiviral effect through restraining NS4B function and could also be used as an anticonvulsant in ...
Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.
GSK-239512 is a histamine H3 receptor antagonist. In Jun 2015, Phase-II for Schizophrenia in USA was discontinued. Phase II clinical trilas for the treatment of...