|Description||OTX008, a calixarene derivative, is a galectin-1 (Gal-1) inhibitor with potential anti-angiogenic and antineoplastic activities. In vitro, OTX008 effects in a panel of human cancer cell lines. In vivo, an ovarian xenograft model was employed to analyse the antitumour activity.|
|Synonyms||Acetamide, 2,2',2'',2'''-[pentacyclo[184.108.40.206,7.19,13.115,19]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-5,11,17,23-tetrayltetrakis(oxy)]tetrakis[N-[2-(dimethylamino)ethyl]-.; OTX-008; OTX 008; OTX008; PTX008; PTX-008; PTX 008; calixarene 0118; N(2dimethylamino)ethyl)acetamidyl calix4arene|
JW 480 has been found to be a potent and selective inhibitor of KIAA1363 (AADACL1), which is a kind of serine hydrolase enzyme.
Gastrodenol is a mineral that is used in treating ulcers and upset stomach.
Phenformin HCl is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class.
Ropidoxuridine is a novel, orally available 5-substituted 2-pyrimidinone-2'-deoxyribonucleoside analogue and prodrug of 5-iododeoxyuridine (IUdR). It has radios...
AEB-1102 is a derivative of human arginase that is more effective and stable for argine levels modulation compared to native human arginase I. It is potentially...
Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease. It consists of polyallylamine that is crosslinked...
Mebeverine Acid is a metabolite of Mebeverine, an antispasmodic. Mebeverine acid appears to be a valuable marker of oral exposure to Mebeverine.
Hydralazine HCl is a hydrochloride salt of hydralazine (Apresoline) that is a direct-acting smooth muscle relaxant with an IC50 of 1.9 mM.