|Description||Org-26576 is a positive allosteric modulator of AMPA receptor. Org-26576 increases the anteroventral and laterodorsal thalamus, cingulate cortex, dentate gyrus and CA3 subfield of the hippocampus in mice. Org-26576 is potentially used for the treatment of depression and attention deficit disorder.|
|Brife Description||AMPA receptor positive allosteric modulator|
|Synonyms||Org-26576; Org26576; Org 26576; (3S)-3,4-Propano-2,3-dihydropyrido[3,2-f][1,4]oxazepine-5(4H)-one|
|Application||potential treatment of depression and attention deficit disorder|
Incubation of LY451395 with Actinoplanes missouriensis NRRL B3342 generated several metabolites that were previously detected in the in vivo metabolism studies ...
GYKI-53784, a dioxolbenzene derivative, has been found to be a AMPA receptor antagonist that could block excitotoxicity and decrease auditory nerve activity at ...
(S)-(-)-5-Fluorowillardiine Hcl is a potent and specific AMPAR agonist.
Farampator, also called as CX-691 or Org24448, is an AMPA receptor positive allosteric modulator and glycine reuptake inhibitor potentially for the treatment of...
The hydrobromide salt form of (RS)-AMPA, which has been found to be an agonist of the excitatory neurotransmitter L-glutamic Acid.
IEM 1925 dihydrobromide
IEM 1925 dihydrobromide is the dihydrobromide salt of IEM 1925, which is a use- and voltage-dependent open-channel antagonist of AMPA receptors. It is selective...
CMPDA is a positive allosteric modulator of AMPA receptors. Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.
Naspm 3HCl is a potent and selective Ca2+ permeable AMPA receptor blocker.