|Description||Optovin is a reversible photoactive TRPA1 activator; stimulates human TRPA1 channels in vitro and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM).|
PPAHV is a non-pungent vanilloid TRPV1 (VR1) receptor agonist (Ki = 3.1 μM), and is agonist at rat VR1(TRPV1) (EC50 between 3 and 10 μM) but virtually inactive ...
ABT 102 is a selective transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with IC50 values to be 5-7 nM. No recent reports of development iden...
RN 9893 hydrochloride
RN 9893 is a potent and selective antagonist of the Transient Receptor Potential ion channel TRPV4 (IC50= 320, 420 and 660 nM for mouse, human and rat channels,...
AMG-9810 is potent, non-vanilloid and selective TRPV1 receptor antagonist with IC50 value of 17 nM. It inhibits capsaicin-, proton-, heat- and endogenous ligand...
TCS 5861528 is a selective TRPA1 blocker with IC50 values are 14.3 and 18.7μM respectively), attenuates diabetes mellitus hypersensitivity and displays antinoci...
Arachidonyl serotonin is a dual target agent of transient receptor potential vanilloid-type I (TRPV1) antagonist and fatty acid amide hydrolase (FAAH) inhibitor...
2-APB, a transient receptor potential (TRP) activator for TRPV1, TRPV2, and TRPV3, could probably be used against diseases caused by hypersensitivity and temper...
A 425619 is a potent and selective TRPV1 antagonist (IC50 = 3-9 nM) that inhibits TRPV1 activation by anandamide and N-arachidonoyl-dopamine. A 425619 exhibits ...