|Description||OPC 13463 is one of the metabolites of pranidipine. Pranidipine is a long acting calcium channel antagonist of the dihydropyridine group.|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
Diltiazem is a calcium channel antagonist. It can relax the smooth muscles in the walls of arteries, allow blood to flow more easily, and lower blood pressure. ...
Nimodipine is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intrac...
S(-)-BAY K 8644
S(-)-BAY K 8644 is an activator of voltage-sensitive L-type calcium channels with positive inotropic, vasoconstrictive and behavioral effects in vivo. It is the...
GV-58, a pupin derivative, has been found to be a P/Q-type Ca²⁺-channel agonist that could be used to against neuromuscular weakness. IC50: 7.21/8.81 uM (N-type...
CI 951 is a dihydronaphthyridine Ca2+ channel antagonist and it may be applicated for the treatment of focal cerebral ischemia. CI 951 has potential as a cerebr...
Penfluridol (Semap, Micefal, Longoperidol) is a highly potent, first generation diphenylbutylpiperidine antipsychotic. It was discovered at Janssen Pharmaceutic...
Efonidipine hydrochloride monoethanolate
The hydrochloride monoethanolate salt form of Efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders.
GAL-021 a novel intravenous BKCa-channel blocker potentially for the treatment of respiratory depression.
NP-118809 is a N-type calcium channel blocker exhibits both anti-allodynic and anti-hyperalgesic activity in the spinal nerve ligation model of neuropathic pain...
TTA-P2 is a selective T-type calcium channel blocker. It blocks T-type currents with an IC50 of 100 nM and stabilized channel in the inactive state in rats DRGs...
Imagabalin acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, which has some selectivity for the α2δ1 subunit over α2δ2. It has anxi...
Felodipine is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM. It can lower blood pressure by reducing peripheral vascular resistance via a highly ...
Dantrolene Sodium, an inhibitor of calcium channel proteins that markedly suppresses the release of calcium previously sequestered by skeletal, but not cardiac,...
Tamolarizin is a calcium antagonist originated by Nippon Chemiphar. Tamolarizin can induce the increase of GABA in the cerebellum and medulla oblongata followin...
Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a p...
Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.
Zonisamide is the first agent of this chemical class to be developed as an antiepileptic drug blocks repetitive firing of voltagesensitive sodium channels and r...
Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.
Ca2+ Channel Agonist 1
A Ca2+ Channel Agonist that selectively acting on N-type Ca2+ channel and also be found to restrain the cdk activity at some extent. IC50: 14.23 uM (EC50, Ca2+ ...
Mibefradil, a calcium channel blocker, has modest selectivity for T-type Ca2+ channels so that could be used in the treatment of sorts of cardiovascular disease...