|Description||Ono-1082 increases cAMP levels in hepatocytes in rats.|
|Synonyms||N-(7-((1R,2R,3R)-2-((1E,3S)-3-((1S,3S)-3-Butylcyclopentyl)-3-hydroxy-1-propenyl)-3-hydroxy-5-oxocyclopentyl)-1,6-dioxoheptyl)-L-leucine;(2S)-2-[[7-[(2R,3R)-2-[(E,3S)-3-(3-butylcyclopentyl)-3-hydroxyprop-1-enyl]-3-hydroxy-5-oxocyclopentyl]-6-oxoheptanoyl]amino]-4-methylpentanoic acid;Ono1082;(S)-2-(7-((1R,2R,3R)-2-((S,E)-3-((1S,3S)-3-butylcyclopentyl)-3-hydroxyprop-1-en-1-yl)-3-hydroxy-5-oxocyclopentyl)-6-oxoheptanamido)-4-methylpentanoic acid|
|Solubility||10 mM in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||752.2±60.0 °C | Condition: Press: 760 Torr|
|Density||1.148±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
Systemic AP20187 administration results in time-dependent LFv2IRE tyrosine phosphorylation and activation of the insulin signaling pathway in both liver and mus...
Neuroblastoma, the most common solid extracranial neoplasm in children, originates from embryonic neural crest cells that usually form the sympathetic ganglia a...
T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflamma...
Amfebutamone (Bupropion) HCl is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4μM for the reuptake of dopamine and norepinephrin...
Cinepazide is a vasodilator. Cinepazide (30 mg/kg, i.v.) potentiated the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, Intr...
NK-122 is a potential bioactive agent.
This active molecular is a cAMP/PKA/CREB pathway activator promoting osteogenic differentiation of human bone marrow derived MSCs in vitro, and it also increase...
DOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection li...
Picaridin，also known as Icaridin, KBR 3023, under the INCI name hydroxyethyl isobutyl piperidine carboxylate, and the trade names Bayrepel and Saltidin, is an i...
Corylin is a major bioactive compound isolated from Psoralea corylifolia L. It is antibiotic or anticancer compound.
Ginsenoside Rb3, a natural triterpenoid saponin, possesses the effect against isoproterenol-induced myocardial injury and heart function impairment, and that th...
Arenobufagin is a bufanolide steroid isolated from the Argentine toad Bufo arenarum. This compound exhibits anticancer chemotherapeutic and anti-angiogenic prop...
KF 13218, a novel pyridobenzazepinone derivative, inhibited human and bovine platelet thromboxane synthase with IC50 values of 27 +/- 5.8 nmol/l (mean +/- S.E.M...
D149 Dye is an organic dye for highly efficient solid-state dye-sensitized solar cells.
1-methyl-7-nitroisatoic anhydride is a reagent which could detect local nucleotide flexibility. It is the most useful reagents for probing 2-hydroxyl reactivity...
CB 3988 is a bio-active chemical compound.
Glyoxalase I inhibitor
Glyoxalase I inhibitor is a potent Glyoxalase I inhibitor, candidate for anticancer agents.
Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties.
Estramustine, a derivative of estradiol, is an alkylating antineoplastic agent that is used in the treatment of prostate cancer throughout the world.
5-R-Rivaroxaban is the R-isomer of Rivaroxaban, which is a novel, oral, direct Factor Xa (FXa) inhibitor. It is useful for antithrombotic agent and is a promisi...