ON123300 - CAS 1357470-29-1
Catalog number: 1357470-29-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C24H27N7O
Molecular Weight:
429.52
COA:
Inquire
Targets:
CDK
Description:
ON123300, a dihydropyrido[2,3-d]pyrimidine derivative, has been found to be an effective multikinase inhibitor that could be probably used against brain tumor and mantle cell lymphomas. It is still under preclinical trials in Colorectal cancer. IC50: 3.8
Purity:
98%
Appearance:
Powder
Synonyms:
UNII-QJ8RO3296G; QJ8RO3296G; CHEMBL3115681; ON123300; SCHEMBL10050883; BDBM50447512
Solubility:
10 mM in DMSO
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
ON123300 has been found to be an effective multikinase inhibitor that could be probably used against brain tumor and mantle cell lymphomas.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
VADOZMZXXRBXNY-UHFFFAOYSA-N
InChI:
InChI=1S/C24H27N7O/c1-29-10-12-30(13-11-29)20-8-6-19(7-9-20)27-24-26-16-18-14-17(15-25)23(32)31(22(18)28-24)21-4-2-3-5-21/h6-9,14,16,21H,2-5,10-13H2,1H3,(H,26,27,28)
Canonical SMILES:
CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C4C=C(C(=O)N(C4=N3)C5CCCC5)C#N
Current Developer:
Icahn School of Medicine at Mount Sinai; Onconova Therapeutics
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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