Omipalisib - CAS 1086062-66-9
Catalog number: 1086062-66-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
Inquire
Targets:
mTOR
Description:
Omipalisib, also known as GSK2126458, is asmall-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity. PI3K inhibitor GSK2126458 binds to and inhibits PI3K in the PI3K/mTOR signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane, increasing mitochondrial membrane permeability and inducing apoptotic cell death. Bax is a member of the proapoptotic Bcl2 family of proteins. PI3K, often overexpressed in cancer cells, plays a crucial role in tumor cell regulation and survival.
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Appearance:
light yellow solid powder
Synonyms:
GSK-2126458; GSK2126458; GSK 2126458; Omipalisib
MSDS:
Inquire
Current Developer:
GSK
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1086062-66-9 Omipalisib

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