|Description||This active molecular is a prostaglandin receptor agonist and detailed information has not been published yet.|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
MK 0524 sodium salt
MK 0524 sodium salt is a potent and selective prostaglandin D2 (PGD2) receptor 1 (DP1) antagonist with Ki values to be 0.57 nM and 750 nM for DP1 and DP2 recept...
GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity (Ki values of 100 nM and 158 nM, resp...
Prostaglandin-E1 is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It can be used as a vasodilator agent increasing pe...
Terutroban is a potent, orally active antagonist of the thromboxane/prostaglandin A2(TP) receptor (IC50 = 16.4 nM). In guinea pigs it also inhibits U 46619 indu...
Carboprost tromethamine is the salt of Carboprost, an analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha). Carboprost activates prostaglandin F ...
PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PG...
Mf-63 is a selective Microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. Its IC50 value is 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, r...
ER 819762 is a potent and selective EP4 receptor antagonist (IC50 = 59 nM) that inhibits EP4-mediated Th1 differentiation, Th17 cell expansion, and IL-23 secret...
This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary dis...
Tafluprost is a novel prostanoid analogue that activates Prostaglandin Receptor. It is used in the treatment of glaucoma and is the first prostanoid to be relea...
CP 544326, also known as taprenepag, is a potent and selective EP(2) receptor agonist. Its EC50 value is 2.8 nM. It is the active acid metabolite of the prodrug...
MF592 is a potent and selective antagonists of the EP4 receptor. It has good functional potency and potent inhibition of PGE2 modulated TNFa release in LPS stim...
ONO 8711 dicyclohexyl amine salt is a selective and competitive prostaglandin E (PGE) receptor EP1 antagonist with chemopreventive activity. It suppresses tumor...
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are cons...
16,16-Dimethyl Prostaglandin E2
16,16-Dimethyl Prostaglandin E2, a prostaglandin E2 derivative, could induce an increase in hematopoietic stem cell (HSC) numbers in mouse model.
BW 245C, a prostaglandin analogue, is a selective prostanoid DP-receptor (DP1)agonist used to treat stroke where the Ki for the inhibition of [3H]-PGD2 binding ...
(+)-Cloprostenol sodium salt
(+)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol, which is an aryl-oxymethyl analog of prostaglandin F2α. It has luteolytic effects and is used ...
FR-181157 is an orally active prostacyclin mimetic that shows high potency and agonist efficacy at the IP receptor.
E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities.
Misoprostol, a synthetic analog of natural prostaglandin E1, is an effective anti-ulcer agent and also has oxytocic properties.