|Description||O-Phospho-L-serine, a molecule which resembles phosphatidylserine head group, is an agonist of the group III metabotropic glutamate receptors mGluR4a and mGluR6 (EC50s = 2-5 µM). It is also used in the purification of the Epstein-Barr virus nuclear antigen 2A.|
|Synonyms||L-Serine-O-phosphate; L-O-PHOSPHOSERINE; L-SERINE-O-PHOSPHATE; L-PHOSPHOSERINE; H-SER(PO3H2)-OH; H-SER(P)-OH; H-SER(H2PO3)-OH; L-2-AMINO-3-HYDROXYPROPANOIC ACID 3-PHOSPHATE; PHOSPHOSERINE; Dexfosfoserine; L-SOP|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
O-Acetyl-L-carnitine hydrochloride is an acetic acid ester of L-carnitine that transports fatty acids into the mitochondria. It was demonstrated that exhibits a...
CPCCOEt has been found to be a mGluR-1 antagonist.
(1S,3R)-ACPD, an isomer of (±)-trans-ACPD, has been found to be an agonist of mGluRs.
NPS 2390 is a Group I mGlu antagonist. NPS 2390 acts as a noncompetitive antagonist of mGluR1 and mGluR5 with IC50 values of 5.2 and 82 nM.
(RS)-MCPG is a non-selective group I/group II metabotropic glutamate receptor antagonist.
ACPT-II has been found to be a mGluR antagonist and could probably exhibit neuroprotective effects.
ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.
VU-0483605, an isoindol derivative, has been found to be a mGluR1 positive allosteric modulator and probably be effective against schizophrenia. EC50: 356 and 3...