NVS-PAK1-1 - CAS 1783816-74-9
Catalog number: B0084-007380
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C23H25ClF3N5O
Molecular Weight:
479.93
COA:
Inquire
Targets:
Others
Description:
NVS-PAK1-1 is potent and specific allosteric PAK1 inhibitor (IC50= 5 nM) with selective over PAK2 and a panel of 442 kinases.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-007380 300 mg $788 In stock
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Brife Description:
A potent and selective allosteric PAK1 inhibitor(IC50= 5 nM)
Synonyms:
NVS-PAK1-1; NVSPAK11; NVS PAK1 1; (3S)-3-[[8-chloro-11-(2,2-difluoroethyl)-3-fluorobenzo[b][1,4]benzodiazepin-6-yl]amino]-N-propan-2-ylpyrrolidine-1-carboxamide
Solubility:
DMSO: ≥125 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
697.8±55.0 ℃ at 760 Torr
Density:
1.42±0.1 g/cm3
InChIKey:
OINGHOPGNMYCAB-INIZCTEOSA-N
InChI:
1S/C23H25ClF3N5O/c1-13(2)28-23(33)31-8-7-16(11-31)29-22-17-9-14(24)3-5-19(17)32(12-21(26)27)20-6-4-15(25)10-18(20)30-22/h3-6,9-10,13,16,21H,7-8,11-12H2,1-2H3,(H,28,33)(H,29,30)/t16-/m0/s1
Canonical SMILES:
CC(C)NC(=O)N1CCC(C1)NC2=NC3=C(C=CC(=C3)F)N(C4=C2C=C(C=C4)Cl)CC(F)F
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CAS 1783816-74-9 NVS-PAK1-1

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