NVP-CGM097 sulfate - CAS 1313367-56-4
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C38H49ClN4O8S
Molecular Weight:
757.34
COA:
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Targets:
MDM-2, p53
Description:
NVP-CGM097 sulfate, a dihydroisoquinolinone derivative, is a potent and selective MDM2 inhibitor (IC50= 1.7±0.1 nM for hMDM2) in the treatment of p53wt tumors.
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Brife Description:
A potent and selective MDM2 inhibitor
Synonyms:
(1S)-1-(4-chlorophenyl)-6-methoxy-2-[4-[methyl-[[4-(4-methyl-3-oxopiperazin-1-yl)cyclohexyl]methyl]amino]phenyl]-7-propan-2-yloxy-1,4-dihydroisoquinolin-3-one;sulfuric acid; NVP-CGM097 (sulfate)
Solubility:
H2O: ≥ 140 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
YFLKIFVIZIALIA-GHVGLMRRSA-N
InChI:
1S/C38H47ClN4O4.H2O4S/c1-25(2)47-35-22-33-28(20-34(35)46-5)21-36(44)43(38(33)27-8-10-29(39)11-9-27)32-16-14-30(15-17-32)41(4)23-26-6-12-31(13-7-26)42-19-18-40(3)37(45)24-42;1-5(2,3)4/h8-11,14-17,20,22,25-26,31,38H,6-7,12-13,18-19,21,23-24H2,1-5H3;(H2,1,2,3,4)/t26?,31?,38-;/m0./s1
Canonical SMILES:
CC(C)OC1=C(C=C2CC(=O)N(C(C2=C1)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N(C)CC5CCC(CC5)N6CCN(C(=O)C6)C)OC.OS(=O)(=O)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1313367-56-4 NVP-CGM097 sulfate

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