|Description||NVP-CGM097 sulfate, a dihydroisoquinolinone derivative, is a potent and selective MDM2 inhibitor (IC50= 1.7±0.1 nM for hMDM2) in the treatment of p53wt tumors.|
|Brife Description||A potent and selective MDM2 inhibitor|
|Synonyms||(1S)-1-(4-chlorophenyl)-6-methoxy-2-[4-[methyl-[[4-(4-methyl-3-oxopiperazin-1-yl)cyclohexyl]methyl]amino]phenyl]-7-propan-2-yloxy-1,4-dihydroisoquinolin-3-one;sulfuric acid; NVP-CGM097 (sulfate)|
|Solubility||H2O: ≥ 140 mg/mL|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradation and p73 activation.
RITA (NSC 652287)
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