NSC134754 - CAS 75041-32-6
Catalog number:
75041-32-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H34N2O2
Molecular Weight:
418.58
COA:
Inquire
Targets:
Others
Description:
NSC134754 is a Heat Shock Factor 1 (HSF1) inhibitor. It can induce inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. NSC134754 can also completely block HIF-1α induced by IGF-1 in HCT116 human colon carcinoma cells.
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Purity:
98%
Appearance:
Powder
Synonyms:
NZ28;(S)-3-ethyl-9,10-dimethoxy-2-(((R)-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Application:
amti-tumor
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Canonical SMILES:
COC1=C(OC)C=C(CCN2CC(CC)=C(C[C@H]3NCCC4=C3C=CC=C4)C[C@]25[H])C5=C1
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