NSC 660028 - CAS 153230-81-0
Catalog number:
153230-81-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H27NO6
Molecular Weight:
461.51
COA:
Inquire
Targets:
Topoisomerase
Description:
NSC 660028, an arylamino etoposide analogue, has been found to be a DNA topoisomerase II inhibitor that was once studied due to its potential anticancer activity.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
NSC660028; NSC-660028; NSC 660028; 2,6-dimethoxy-4-((5S,5aS,8aR,9R)-9-(phenylamino)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl)phenol
Storage:
Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
MSDS:
Inquire
Quality Standard:
In-house standard
Quantity:
Milligram-Grams
Canonical SMILES:
[H][C@@]12COC[C@@]([C@H](C3=C(C=C4OCOC4=C3)[C@@H]2NC5=CC=CC=C5)C(C=C6OC)=CC(OC)=C6O)1[H]
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Topoisomerase Products


CAS 72496-41-4 Pirarubicin

Pirarubicin
(CAS: 72496-41-4)

Pirarubicin is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an ant...

CAS 867063-97-6 Atiratecan

Atiratecan
(CAS: 867063-97-6)

Atiratecan is a topoisomerase inhibitor. It has potential anticancer activity.

CAS 151271-53-3 UK-1

UK-1
(CAS: 151271-53-3)

UK-1, a benzoxazol derivative, has been found to a Streptomyces metabolite that could exhibit anticancer activity and topoisomerase II restraination activity.

CAS 308246-52-8 LMP744

LMP744
(CAS: 308246-52-8)

LMP744, also known as NSC706744, is a novel indenoisoquinoline topoisomerase I inhibitor.

CAS 86639-52-3 SN-38

SN-38
(CAS: 86639-52-3)

SN-38 is the active metabolite of irinotecan. In vitro cytotoxicity assays show that the potency of SN-38 relative to irinotecan varies from 2- to 2000-fold. SN...

CAS 54301-15-4 Amsacrine hydrochloride

Amsacrine hydrochloride
(CAS: 54301-15-4)

Amsacrine hydrochloride is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specif...

CAS 446-72-0 Genistein

Genistein
(CAS: 446-72-0)

Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by ...

CAS 519-23-3 Ellipticine

Ellipticine
(CAS: 519-23-3)

Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor. Ellipticine is also a natural product, isolated in 1959 from the Australian everg...

CAS 169869-90-3 Exatecan Mesylate

Exatecan Mesylate
(CAS: 169869-90-3)

Exatecan Mesylate (DX-8951) is a totally synthetic analogue of the topoisomerase I-inhibitor camptothecin, which was synthesised to impart increased aqueous sol...

CAS 211100-13-9 Sabarubicin

Sabarubicin
(CAS: 211100-13-9)

Sabarubicina, a disaccharide analogue of doxorubicin, is an antineoplastic agent which can intercalate into the DNA of tumor cells and interact with topoisomera...

CAS 100286-90-6 Irinotecan hydrochloride

Irinotecan hydrochloride
(CAS: 100286-90-6)

Irinotecan Hcl(CPT-11 Hcl) prevents DNA from unwinding by inhibition of topoisomerase 1.

CAS 175414-77-4 Voreloxin

Voreloxin
(CAS: 175414-77-4)

Voreloxin(SNS-595; AG 7352) is a small molecule and a naphthyridine analogue with antineoplastic activity; inhibitor of Topo II.

CP 117227
(CAS: 154531-78-9)

CP 117227, a dibenzocyclohepten derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in studies of anticancer.

CAS 174634-08-3 TAS-103

TAS-103
(CAS: 174634-08-3)

TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS-103 has been reported to be ...

CAS 78186-34-2 Bisantrene Dihydrochloride

Bisantrene Dihydrochloride
(CAS: 78186-34-2)

Bisantrene Dihydrochloride is the hydrochloride salt of Bisantrene. Bisantrene, also referred to CL-216942, Cyabin or NSC-337766, an anthracene bishydrazone der...

CAS 1562067-05-3 Banoxantrone D12

Banoxantrone D12
(CAS: 1562067-05-3)

The deuterium labeled banoxantrone which was rationally designed to have anti-tumor activity following bioreduction by tissue cytochrome P450 to AQ4, an active ...

CAS 65271-80-9 Mitoxantrone

Mitoxantrone
(CAS: 65271-80-9)

Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. It is used in the treatment of certai...

CAS 51264-14-3 Amsacrine

Amsacrine
(CAS: 51264-14-3)

Amsacrine is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibit...

CAS 4707-32-8 β-Lapachone

β-Lapachone
(CAS: 4707-32-8)

β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae), exhibiting anti-inflammatory properties by suppr...

CAS 123948-87-8 Topotecan

Topotecan
(CAS: 123948-87-8)

Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...

Quick Inquiry

Verification code

Featured Items