|Description||NS 1643 is human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM)|
|Solubility||Soluble in DMSO|
|Storage||Store at -20 °C|
|Application||KV11.1 channel activator|
|Quality Standard||Enterprise Standard|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
Sematilide, also known as CK-1752, is a class III antiarrhythmic compound showing selective delayed rectifier K+ current channel blocking. It inhibits rapidly a...
Mitiglinide calcium hydrate
Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist.
GYKI-16638 is Potassium channel and Sodium channel antagonist originated by Nonindustrial source. It is a novel antiarrhythmic agent.
This active molecular is a Kv1.5 potassium channel inhibitor originated by Bristol-Myers Squibb. Treatment for paroxysmal atrial fibrillation is in Phase II cli...
ZM 260384, a benzoxazine derivative, has been found to be a potassium channel agonist that was once studied against hypertension and thrombus.
Doxapram HCl inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
Senicapoc, previously called as ICA 17043, is a is a small organic potent and selective blocker of the Gardos channel which is the calciumactivated potassium ch...
BMS-191095 is an activators that has selective effects on mitochondrial ATP-sensitive potassium (mitoKATP) channels. in vitro: induces mitochondrial-depolarizat...
Indapamide is a thiazide-like diuretic drug marketed by Servier, generally used in the treatment of hypertension, as well as decompensated heart failure. Combin...
Celikalim is s ATP-sensitive potassium channel agonist originated by Wyeth. It increases K+ outward flux in dog and human airway smooth muscle. But clinical tri...
Flupirtine maleate is the salt form of Flupirtine, which is a centrally acting non-opioid analgesia, is a selective neuronal potassium channel opener that also ...
This active molecular is a selective renal outer medullary potassium channel (RMOK) inhibitor originated by Merck Sharp & Dohme for the treatment of hypertensio...
Way 123398 is a class III antiarrhythmic agent. It is a Potassium channel antagonist originated by Wyeth. No preclinical development for Arrhythmias in USA was ...
Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. Glipizide is used to treat high blood sugar levels caused by a type...
Carabersat, also called as SB 204269, an orally-effective anticonvulsant agent, is an ATP-sensitive potassium channel (K-ATP) opener with potential effect to t...
NS6180 is a potent KCa3.1 channel blocker (IC50 values are 9, 14 and 15 nM for rat, human and mouse erythrocyte KCa3.1 channels respectively). NS6180 prevents T...
AZD0837 is an oral direct thrombin inhibitor currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial ...
Glyburide (Glibenclamide) is an anti-diabetic compound in a class of medications known as sulfonylureas, closely related to sulfa agents.
Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth.
TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretio...