NPS-2143 hydrochloride - CAS 324523-20-8
Catalog number: 324523-20-8
Category: Inhibitor
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Molecular Formula:
C24H26Cl2N2O2
Molecular Weight:
445.38
COA:
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Targets:
CaSR
Description:
NPS-2143 (SB-262,470A) is a calcilytic drug which acts as an antagonist at the Calcium-sensing receptor (CaSR), and consequently stimulates release of parathyroid hormone. Calcilytic drugs have been researched as potential treatments for osteoporosis, and as the first such compound developed, NPS-2143 is still widely used in research into the CaSR receptor as well as design of newer calcilytic agents.
Purity:
>98%
Synonyms:
NPS2143 hydrochloride; NPS 2143 hydrochloride
MSDS:
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InChIKey:
ZEBNDUQLNGYBNL-VEIFNGETSA-N
InChI:
InChI=1S/C24H25ClN2O2.ClH/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26;/h3-12,20,27-28H,13,15-16H2,1-2H3;1H/t20-;/m1./s1
Canonical SMILES:
CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O.Cl
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