|Description||Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.|
Fenspiride is an α adrenergic and H1 histamine receptor antagonist. It is an oxazolidinone spiro compound. It is used as a drug in the treatment of certain resp...
Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.
Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.
Brompheniramine hydrogen maleate
Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
Histamine is an organic nitrogenous compound produced by basophils and by mast cells found in nearby connective tissues.
The hydrochloride salt form of Chlorcyclizine which could be used as an antihistamine agent and is also found to have anticholinergic effect at some extent.
ABT-239 is a novel, highly efficacious, non-imidazole class of H3R antagonist has been investigated as a treatment for ADHD, Alzheimer's disease, and schizophr...
JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other h...
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.
Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.
Dexchlorpheniramine maleate, also known as Polaramine, is an antihistamine to treat allergic conditions, urticaria and allergic conjunctivitis and pruritus.
Ciproxifan maleate, also called as FUB-359 maleate, is a highly potent and strongly selective histamine H3 inverse agonist/antagonist (IC50 = 9.2 nM) which disp...
Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine. It is a racemic selective H1 receptor inverse agonist. It is used in cutane...
GSK-189,254 is a H3 histamine receptor inverse agonist. It has subnanomolar affinity for the H3 receptor with Ki of 0.2nM. It possesses stimulant and nootropic ...
Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM.
The hydrochloride salt form of Clemizole that has hepatitis C antiviral effect through restraining NS4B function and could also be used as an anticonvulsant in ...
Bavisant dihydrochloride is the dihydrochloride form of Bavisant, which is a highly selective, orally active antagonist of the human H3 receptor. It may be used...
This active molecular is a imidazolylpropylguanidine type compound as a hH4R agonist (histamine H4 receptor agonist) showing negligible hH1R and hH2R activities...
Hydroxyzine (sold as Vistaril, Atarax) is a first-generation antihistamine of the diphenylmethane and piperazine class.
JNJ10181457 dihydrochloride is a selective non-imidazole brain penetrant histamine H3 receptor antagonist with pKi values of 8.15 and 8.93 for rat and human H3 ...