Nintedanib - CAS 656247-17-5
Catalog number:
B0084-262244
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C31H33N5O4
Molecular Weight:
539.62
COA:
Inquire
Targets:
FGFR
Description:
Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. It exhibits potential antiangiogenic and antineoplastic activities.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-262244 500 mg $279 In stock
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Brife Description:
inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β
Purity:
>98%
Synonyms:
Vargatef; BIBF-1120; BIBF 1120; Intedanib
Solubility:
Water: 9.66 mg/L
MSDS:
Inquire
Application:
the treatment of idiopathic pulmonary fibrosis
InChIKey:
XZXHXSATPCNXJR-ZIADKAODSA-N
InChI:
InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-
Canonical SMILES:
CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)NC(=C3C4=C(C=C(C=C4)C(=O)OC)NC3=O)C5=CC=CC=C5
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Chemical Structure

CAS 656247-17-5 Nintedanib

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