NIH-12848 - CAS 959551-10-1
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H14F3N3S
Molecular Weight:
385.41
COA:
Inquire
Targets:
Others
Description:
NIH-12848 is putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor (IC50= 1 μM) but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM.
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Brife Description:
A putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor (IC50= 1 μM)
Synonyms:
N-(thiophen-2-ylmethyl)-2-[2-(trifluoromethyl)phenyl]quinazolin-4-amine; NCGC00012848-02; NIH-12848; NCGC00012848-02
Solubility:
DMSO: ≥ 28 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
441.6±45.0 ℃ at 760 Torr
Density:
1.384±0.06 g/cm3
InChIKey:
QBDAEJRHUCSSPR-UHFFFAOYSA-N
InChI:
1S/C20H14F3N3S/c21-20(22,23)16-9-3-1-7-14(16)19-25-17-10-4-2-8-15(17)18(26-19)24-12-13-6-5-11-27-13/h1-11H,12H2,(H,24,25,26)
Canonical SMILES:
C1=CC=C(C(=C1)C2=NC3=CC=CC=C3C(=N2)NCC4=CC=CS4)C(F)(F)F
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Chemical Structure

CAS 959551-10-1 NIH-12848

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