|Description||Niclosamide is an oral antihelminthic drug, which has been used to treat tapeworm infection for about 50 years. Niclosamide is also used as a molluscicide for water treatment in schistosomiasis control programs. Recently, several groups have independently discovered that niclosamide is also active against cancer cells. Evidence supports that niclosamide targets multiple signaling pathways (NF-κB, Wnt/β-catenin, Notch, ROS, mTORC1, and Stat3), most of which are closely involved with cancer stem cells. Given its potential antitumor activity, clinical trials for niclosamide and its derivatives are warranted for cancer treatment.|
|Appearance||A crystalline solid|
Tilbroquinol is an antiprotozoal agent effective against amoebiasis. It has been used against Vibrio cholerae.
N,N-Diethyl-3-methylbenzamide, a benzamide derivative, could be a significant additive in vermifuge.
Clorsulon is used in the treatment of Fasciola hepatica infections in calves and sheep.
SK369796, also known as N-tert-butylisoquine, shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 str...
Azithromycin is an antibiotic for inhibition of parasite growth with IC50 of 8.4 μM.
3,5-Dinitrobenzamide is an anti-parasitic agent.
Bephenium is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.
Spirodiclofen, a tetronic acid derivative, is a broad spectrum acaricide.
Pyrantel is used to study neuronal nicotinic receptors and has been is used to treat parasiticinfections in livestock. Pyrantel tartrate salt is used to study a...
Oxantel Pamoate is used as an anthelmintic. It has typically been used human and animal use as a standard treatment for intestinal worms. lt may be used as a fu...
Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazen...
Eprinomectin(MK-397) is an avermectin selected for development as a topical endectocide; has anthelmintic, insecticidal and miticidal activity.
Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis, which belongs to B-type AChR activato...
Fexinidazole is effective against trypanosomes caused by infection with species of the protozoan parasite Trypanosoma brucei.
Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. It is a macrocyclic lactone that makes ...
Chlorthal-dimethyl, also called as Dacthal, it is metabolized in animals to monomethyl ester and chlorthal which are eliminated in urine and used as a pesticide...
Naphthoquine phosphate and artemisinine are two antimalarials developed in China. Both drugs have proven to be efficacious and well tolerated as monotherapy as ...
Pyrantel pamoate is used as a deworming agent in domesticated animals such as horses, hamsters, sheep, pigs, cats, and dogs. It is a combination of pyrantel and...
Oxibendazole is a broad-spectrum anthelmintic
GNF179 exhibits a low clearance (CL=22 ml/min/kg, ~25% of hepatic blood flow in mice), a large volume of distribution (steady-state volume of distribution, Vss=...