Nexturastat A - CAS 1403783-31-2
Catalog number: 1403783-31-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
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Targets:
HDAC
Description:
Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50= 5.02 +/- 0.60 nM). Nexturastat A possesses antiproliferative effects against melanoma cells. Histone deacetylases (HDACs) mediate regulation of gene expression via changes in nucleosome conformation. Dysregulation of histone acetylation can lead to the development of cancers. There is renewed interest in capitalizing new breakthroughs in epigenetic research to address oncology therapy.
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Purity:
0.98
Appearance:
white solid powder
Synonyms:
Nexturastat A
MSDS:
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CAS 1403783-31-2 Nexturastat A

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