|Description||Nemonapride, an atypical antipsychotic approved in Japan for the treatment of schizophrenia, is a highly potent dopamine D2-like receptor antagonist, which is selective over D1-like receptors (Ki= 0.1 and 740 nM for D2-like and D1-like receptors respectively). Nemonapride also binds sigma 1 (σ1) and σ2 receptors (Kis = 8.4 and 9.6 nM, respectively) and activates the serotonin 1A receptor (5-HT1A; IC50 = 34 nM).|
|Purity||≥99% by HPLC|
|Synonyms||rel-5-Chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phennylmethyl)-3-pyrrolidinyl]benzamide; cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1- (phennylmethyl)-3-pyrrolidinyl]benzamide; Emilace; Emonapride; YM 09151; YM09151; YM-09151; YM 09151-2|
|Solubility||ethanol to 20 mM; DMSO to 25 mM|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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