Nemonapride - CAS 75272-39-8
Category: Inhibitor
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Molecular Formula:
C21H26ClN3O2
Molecular Weight:
387.91
COA:
Inquire
Targets:
Dopamine Receptor
Description:
Nemonapride, an atypical antipsychotic approved in Japan for the treatment of schizophrenia, is a highly potent dopamine D2-like receptor antagonist, which is selective over D1-like receptors (Ki= 0.1 and 740 nM for D2-like and D1-like receptors respectively). Nemonapride also binds sigma 1 (σ1) and σ2 receptors (Kis = 8.4 and 9.6 nM, respectively) and activates the serotonin 1A receptor (5-HT1A; IC50 = 34 nM).
Purity:
≥99% by HPLC
Appearance:
White solid
Synonyms:
rel-5-Chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phennylmethyl)-3-pyrrolidinyl]benzamide; cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1- (phennylmethyl)-3-pyrrolidinyl]benzamide; Emilace; Emonapride; YM 09151; YM09151; YM-09151; YM 09151-2
Solubility:
ethanol to 20 mM; DMSO to 25 mM
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
KRVOJOCLBAAKSJ-RDTXWAMCSA-N
InChI:
InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m1/s1
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CAS 75272-39-8 Nemonapride

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