|Description||Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29, which significantly decreases BV6/DAC-induced cell death in MV4-11 cells. It prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors.|
|Purity||≥98% by HPLC|
|Solubility||DMSO to 20 mM|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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