|Description||Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.|
|B0084-117868||100 mg||$189||In stock|
SPD 304 a cell-permeable inhibitor of tumor necrosis factor-α (TNFα, IC50 = 22 μM), which is a modulator of inflammation conditions such as rheumatoid arthritis...
Hispidol ((Z)-Hispidol) inhibits TNF-α induced adhesion of monocytes to colon epithelial cells (IC50= 0.50 µM) and is a potential therapeutic for inflammatory b...
Beta-mangostin, a natural product extracted from the fruits of Garcinia mangostana, can reduced the levels of TNF-α and IL-1β in peritoneal fluid.
Bioymifi is a potent and selective death receptor 5 (DR5) activator. Bioymifi works by mimicking the ability of TRAIL to stimulate clustering of DR5, triggering...
Pomalidomide inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respecti...
BMS561392 is a tumor necrosis factor-alpha (TNF alpha) converting enzyme inhibitor. It has the potential treatment of diseases characterized by overproduction o...
Necrostatin 2 S enantiomer
Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin, which is a potent necroptosis inhibitor.
Necrostatin 2 is a potent necroptosis inhibitor. It is a potent in vitro necroptosis inhibitors and is also efficacious in an animal model of ischemic stroke.
A potent, orally active and dual inhibitor of phosphodiesterase 4 (PDE4) (IC50= 1.1 μM) and tumor necrosis factor-α (TNF-α) (IC50= 2.5 μM).
Lenalidomideis a derivative of thalidomide introduced in 2004. Lenalidomide (Revlimid, CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM.
DCVC has been found to influence sort of cytokines release stimulated by pathogen.
Necrostatin 2 racemate
Necrostatin 2 racemate is the racemate of Necrostatin, which is a potent necroptosis inhibitor.
GW-3333 is a dual inhibitors of tumor necrosis factor-alpha (TNF)-Converting Enzyme (TACE) and matrix metalloproteinases.
CPI-1189 is an inhibitor of TNF-α release with the potential use to treat sciatica and postherpetic neuralgia.
Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.
Lenalidomide strongly induces IL-2 and sIL-2R production. Lenalidomide-induced tyrosine phosphorylation of CD28 on T cells is followed by a down-stream activati...
C 87 is a TNF-α inhibitor (Kd = 110 nM for hTNF-α). It was shown to inhibit TNF-α-induced cytotoxicity in L929 fibroblast cells, attenuate inflammation and incr...
Roquinimex, also known as LS 2616 and FCF89 (brande name: Linomide), is a quinoline-3-carboxamide with potential antineoplastic activity. Roquinimex inhibits en...
Magnolol is a bioactive lignin found in Magnolia officinalis and acts as a TNF-α and nitric oxide (NO) inhibitor. It exhibits potential therapeutic effect on an...
Lenalidomide is a TNF-α secretion inhibitor.