ND-630 - CAS 1434635-54-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C28H31N3O8S
Molecular Weight:
569.63
COA:
Inquire
Targets:
Others
Description:
ND-630, also called as NDI 010976, is a highly selective, reversible inhibitor of acetyl-CoA carboxylase (ACC) and had IC50 values of 2 and 7 nM for ACC1 and 2, respectively, EC50 values in HepG2 serum free and 10% serum of 9 and 66 nM, respectively, and 2-fold C2C12 fatty acid oxidation (FAOxn) stimulation at 200 nM.
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Brife Description:
An acetyl-CoA carboxylase (ACC) inhibitor
Synonyms:
2-[1-[(2R)-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxothieno[2,3-d]pyrimidin-3-yl]-2-methylpropanoic acid
Solubility:
DMSO: ≥ 50 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
779.0±70.0 ℃ at 760 Torr
Density:
1.42±0.1 g/cm3
InChIKey:
ZZWWXIBKLBMSCS-FQEVSTJZSA-N
InChI:
1S/C28H31N3O8S/c1-16-21-24(32)31(28(2,3)26(33)34)27(35)30(25(21)40-22(16)23-29-11-14-38-23)15-20(39-17-9-12-37-13-10-17)18-7-5-6-8-19(18)36-4/h5-8,11,14,17,20H,9-10,12-13,15H2,1-4H3,(H,33,34)/t20-/m0/s1
Canonical SMILES:
CC1=C(SC2=C1C(=O)N(C(=O)N2CC(C3=CC=CC=C3OC)OC4CCOCC4)C(C)(C)C(=O)O)C5=NC=CO5
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1434635-54-7 ND-630

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