ND-630 - CAS 1434635-54-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
ND-630, also called as NDI 010976, is a highly selective, reversible inhibitor of acetyl-CoA carboxylase (ACC) and had IC50 values of 2 and 7 nM for ACC1 and 2, respectively, EC50 values in HepG2 serum free and 10% serum of 9 and 66 nM, respectively, and 2-fold C2C12 fatty acid oxidation (FAOxn) stimulation at 200 nM.
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Brife Description:
An acetyl-CoA carboxylase (ACC) inhibitor
2-[1-[(2R)-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxothieno[2,3-d]pyrimidin-3-yl]-2-methylpropanoic acid
DMSO: ≥ 50 mg/mL
Store in a cool and dry place (or refer to the Certificate of Analysis).
Boiling Point:
779.0±70.0 ℃ at 760 Torr
1.42±0.1 g/cm3
Canonical SMILES:
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1434635-54-7 ND-630

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