NCB-0846 - CAS 1792999-26-8
Catalog number: B0084-007723
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C21H21N5O2
Molecular Weight:
375.42
COA:
Inquire
Targets:
Wnt
Description:
NCB-0846 is an orally available, first-in-class TNIK inhibitor (IC50= 21 nM) and shows marked anti-tumour and anti-CSC activities.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-007723 300 mg $688 In stock
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Brife Description:
An orally available TNIK inhibitor (IC50= 21 nM)
Synonyms:
NCB-0846; NCB 0846; NCB0846; 4-[2-(3H-benzimidazol-5-ylamino)quinazolin-8-yl]oxycyclohexan-1-ol
Solubility:
DMSO: ≥ 30 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
726.2±70.0 ℃ at 760 Torr
Density:
1.415±0.06 g/cm3
InChIKey:
FYWRWBSYRGSWIQ-UHFFFAOYSA-N
InChI:
1S/C21H21N5O2/c27-15-5-7-16(8-6-15)28-19-3-1-2-13-11-22-21(26-20(13)19)25-14-4-9-17-18(10-14)24-12-23-17/h1-4,9-12,15-16,27H,5-8H2,(H,23,24)(H,22,25,26)
Canonical SMILES:
C1CC(CCC1O)OC2=CC=CC3=CN=C(N=C32)NC4=CC5=C(C=C4)N=CN5
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NCB-0846 is an orally available, first-in-class TNIK inhibitor (IC50= 21 nM) and shows marked anti-tumour and anti-CSC activities.

Chemical Structure

CAS 1792999-26-8 NCB-0846

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