|Description||Nav1.7-IN-2, a voltage-gated sodium channels, could be probably effective in chronic pain therapy. IC50: 80 nM.|
|Solubility||10 mM in DMSO|
|Application||Nav1.7-IN-2 is a voltage-gated sodium channels and could be probably effective in chronic pain therapy.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
T-1095, with potential antidiabetic effect, is an inhibitor of renal Na+-glucose cotransporters that may provide a novel way to treating diabetes.
Nav1.7 inhibitor is a Voltage-gated sodium channel inhibitor that have probable effect in pain therapy and local anaesthesia.
Amiloride, a pyrazine derivative potassium-sparing diuretic, is a blocker of sodium channel in renal epithelial cells. Amiloride blocked the low threshold Ca2+ ...
This active molecular is a calcium channel antagonist with sodium channel stimulating property as a dihydropyridine. PD 122860 can increase left ventricular con...
Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50...
Sodium Channel inhibitor 1
Sodium Channel inhibitor 1, a 3-Oxoisoindoline-1-carboxamide derivative, is an effective voltage-gated sodium channel blocker that could be used for pain treatm...
Eleclazine is a selective Sodium channel antagonist. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and en...
XEN907 is a novel spirooxindole NaV1.7 blocker with IC50 of 3 nM. It shows a further 10-fold increase in potency, which represents a promising structure for fur...
CGP-47292, a triazole compound, has been found to be a metabolite of CGP-33101 that could be used agaist Lennox-Gastaut syndrome as a Sodium Channel antagonist.
Vinpocetine is a Phosphodiesterase inhibitor and selective for PDE1. It also blocks voltage-gated Na+ channels.
Ethotoin is an anticonvulsant drug. It is a sodium channel inhibitor. Ethotoin can be used for the treatment of epilepsy. It is a hydantoin, similar to phenytoi...
(-)-Sparteine sulfate pentahydrate
(-)-Sparteine sulfate pentahydrate is an alkaloid compound which could be used as in the treatment of antiarrhythmic by blocking sodium channel.
Ropivacaine hydrochloride is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
Mephenytoin is known to target sodium channel protein type 5 subunit alpha. It is a hydantoin-derivative anticonvulsant used to control various partial seizures...
Riluzole is a drug used to treat amyotrophic lateral sclerosis.
Raxatrigine is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. It acts as a selective, small-molecule, sta...
Funapide is a Nav1.7 and Nav1.8 voltage-gated sodium channel inhibitor under the development by Xenon Pharmaceuticals and Teva Pharmaceutical Industries. It is ...
Carbamazepine (Carbatrol) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.Carbamazepine (CBZ), first marketed under the tradename Tegr...
Moricizine, a Phenothiazine derivative, is effective in suppressing premature ventricular contractions, couplets, and nonsustained ventricular tachycardia. And ...
Dyclonine HCl is a hydrochloride salt form of dyclonine which is an oral anaesthetic.