|Description||Nateglinide(Starlix) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of the β cells.|
Y-29794 is an orally active, potent and specific non-peptide inhibitor of prolyl endopeptidase, a serine peptidase that may be implicated in the biosynthesis of...
Astragaloside II is a saponin found in the root of Astragalus membranaceus (Fisch.) Bunge, which is known as huáng qí in Traditional Chinese Medicine. It has ca...
Glycitein is a soybean (yellow cultivar) isoflavonoid. It may be used to study anti-oxidation processes at the level of gene transcription where it increases th...
CFI-401870, an azabicyclo derivative, has been found to be a TTK inhibitor that could be significant in anticancer studies. IC50 < 10 nM.
Nortriptyline hydrochloride is a second-generation tricyclic antidepressant (TCA) marketed as the hydrochloride salt under the trade names Sensoval, Aventyl and...
Sonoflora 1, a kind of PDT photosensitivizer, was once studied against breast cancer and the Phase I/II trial has been already discontinued by SonneMed.
Chitinase-IN-1 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20uM compound concentration's inhibitory percentage are 75%...
Nateglinide(Starlix) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas. It achieves this by clo...
Quetiapine metabolite Quetiapine sulfoxi
Quetiapine metabolite Quetiapine sulfoxide, a metabolite of Quetiapine, has antipsychotic effect.
PD-116152 is a novel and highly substituted phenazine. It has antitumor activity. It was isolated from the culture broth of a Streptomyces sp.
Oroxylin A possessed abilities of inhibiting the ATRA-induced IL-6 production via modulation of LAP/LIP/CHOP in leukemia cell lines, which could providing a the...
ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold se...
Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activ...
Aminophenazone (or aminopyrine) is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of agranulocytosis.
NSC659000 is a potential antifungal agent. It is one of the 3-(3-methyl-5-isoxazolyl)-2-styrylquinazolin-4(3H)-ones derivatives that be synthesized for antifung...
Desmopressin acetate, also know as DDAVP, has been found to be a vasopressor agent that could exhibit antidiuretic activity and probably be useful in improving ...
CC122 is a novel agent for DLBCL. It is an orally available pleiotropic pathway modulator. It has antitumor and immunomodulatory activity. It is used for the tr...
Ocaphane is a strong antitumor agent used on a number of animal tumors along with fairly toxic to hemopoietic organs.
Antitumor Compound 1
Antitumor Compound 1 is a potent compound which comprises a new imidazopyridine having excellent antitumor activity as an active ingredient.
BPTES is a potent and selective Glutaminase GLS1 (KGA) inhibitor with IC50 of 0.16 μM.