|Description||A poliamine amide as potent Spermidine uptake inhibitor.|
IEM 1460, an adamantane derivative, is a selective and voltage-dependent open-channel antagonist of AMPA receptors. It is Ca2+ permeable and lacks GluR2 subunit...
GYKI 47261 dihydrochloride
This active molecular is Non-competitiv a AMPA antagonist with IC50 value of 2.5 μM. GYKI-47261 is also a CYP2E1 inducer. GYKI-47261 showed broad spectrum of an...
CMPDA is a positive allosteric modulator of AMPA receptors. Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.
LY 404187 is an allosteric modulator of AMPA receptors (IC50 = 0.15μM, 0.21μM, 1.66μM and 5.65 μM for GluA2i, GluA4i, GluA3i and GluA1i, respectively).
This active molecular is an AMPA receptor antagonist which blocks AMPA receptors in 10-20µM concentrations. It is also a Glutamate receptor antagonist. NBQX was...
CX 614 has been found to be an AMPA modulator and has also been found to be an ampakine drug facilitating activation of glutamatergic AMPA receptors.
The (S)- but not (R)-isomers of willardiine and 5-bromowillardiine were potent agonists, producing rapidly but incompletely desensitizing responses. At a concen...
CNQX disodium salt
The sodium salt form of CNQX, which is an AMPA/kainate antagonist and could be used in studies of neurological disorders or damage.