|Description||Naronapride is a selective 5-HT(4) receptor agonist for gastrointestinal motility disorders. It can accelerate overall colonic transit and tend to accelerate GE and AC emptying and loose stool consistency. In Nov 2016, Renexxion planed two phase III trials for Constipation in USA.|
|Synonyms||860169-57-9(dihydrochloride); ATI7505; (R)-quinuclidin-3-yl 6-((3S,4R)-4-(4-amino-5-chloro-2-methoxybenzamido)-3-methoxypiperidin-1-yl)hexanoate|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Current Developer||ARYx Therapeutics|
Risperidone is a serotonin 5-HT2 receptor blocker and a potent dopamine D2 receptor antagonist.
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Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B re...
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LY 302148 is a 5-HT1F receptor agonist with potential for migraine therapeutics.
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Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.
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Quetiapine sulfoxide dihydrochloride
Quetiapine sulfoxide dihydrochloride, a metabolite of Quetiapine, has antipsychotic effect.
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SB742457 is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.It was under development by GlaxoSmithKline f...
BMS 181101, an indole derivative, has been found to be a 5-HT receptor agonist that could be probably effective against depression and also restrain serotonin r...
The hydrochloride salt form of Iloperidone which is a antagonist of both D2 and 5-HT2 receptor and has been commonly used against schizophrenia. IC50: 10-100 nm...
Aripiprazole lauroxil is a Dopamine D2 receptor agonist, Serotonin 1A receptor agonist and ISerotonin 2A receptor antagonist under the development of Alkermes p...