|Description||Naratriptan, a 5-HT1B/1D receptor agonist, could be used in the treatment of migraine.|
|Solubility||DMSO 74 mg/mL (198 mM); Water 22 mg/mL (59 mM)|
|Application||Naratriptan is a 5-HT1B/1D receptor agonist that could be used in the treatment of migraine.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
|Boiling Point||541.3ºC at 760 mmHg|
Mosapride Citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and ...
LY 344864 racemate
LY 344864 racemate is a 5-HT1F receptor agonist.
The mesylate salt form of Dolasetron which is a pseudopelletierine derivative and could be used to relieve the nausea and vomiting caused by chemotherapy for be...
The hydrobromide salt form of NAN-190 which is an effective antagonist of 5-HT1A serotonin receptor.
Pindolol, an Indole derivative, could be used in the treatment of hypertension and arrhythmia for acting as a 5-HT1A/1B receptor antagonist. IC50: 33nM(Ki).
Thioproperazine is a potent neuroleptic with antipsychotic properties, for the treatment of all types of acute and chronic schizophrenia, including those which ...
Pizotifen Malate is a benzocycloheptane based agent used for recurrent migraine headaches.
Nefazodone is a selective serotonin 5-HT2 receptor antagonist. It is an antidepressant under the development of Bristol-Myers Squibb. Its sale was discontinued ...
Quetiapine, an thiazepin-analogue of Clozapine, could be effective in the treatment for schizophrenia and major depressive disorder for behaving as a 5HT-2 and ...
Mirisetron maleate, an oxoquinoline derivative, has been found to be a 5-HT3 receptor antagonist that could probably be effective against anxiety disorders and ...
Prucalopride, also known as R-108512, is a selective, high affinity serotonin (5-HT4) receptor agonist with enterokinetic activities. Prucalopride alters coloni...
Asenapine is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania ...
Dolasetron, a pseudopelletierine derivative, is a 5-HT3 receptor antagonist that could be used to relieve the nausea and vomiting caused by chemotherapy.
Velusetrag is a selective, 5-HT4receptor agonist. Phase II clinical trials for the treatment of gastroparesis are on-going. Clnical trials for Alzheimer's disea...
Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B re...
Granisetron is an antagonist of serptpmom 5-HT3 receptor and could be used to relieve the nausea and vomiting symptom after receving chemotherapy by decreasing ...
Agomelatine L(+)-Tartaric acid
Agomelatine L(+)-Tartaric acid is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. It is used as an ant...
LY 344864 is a brain penetrant, full agonist that specifically targets 5-HT1F receptor (pKi = 8.2) with > 80-fold selectivity over other serotonin receptors (Ki...
Pardoprunox, also called as SLV308 or DU-126891, is a D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A rec...